文献名： A PTFE helical capillary microreactor for the high throughput synthesis of monodisperse silica particles

作者：Hui Yangab; Eser Metin Akinogluca; Lijing Guoa; Mingliang Jina; Guofu Zhouab; Michael Giersigad; Lingling Shuiae; Paul Mulvaneyca 

aInternational Academy of Optoelectronics at Zhaoqing, South China Normal University, Zhaoqing, 526238 Guangdong, PR China

bGuangdong Provincial Key Laboratory of Optical Information Materials and Technology & Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou 510006, PR China

cARC Centre of Excellence in Exciton Science, School of Chemistry, University of Melbourne, Parkville, VIC 3010, Australia

dInstitute of Fundamental Technological Research, Polish Academy of Sciences, 02-106 Warsaw, Poland

eSchool of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006 Guangdong, PR China

摘要：We propose a simple and inexpensive SiO2 submicron particle synthesis method based on a PTFE helical capillary microreactor. The device is based on Dean flow mediated, ultrafast mixing of two liquid phases in a microfluidic spiral pipe. Excellent control of particle size between 100 nm and 600 nm and narrow polydispersity can be achieved by controlling the device and process parameters. Numerical simulations are performed to determine the optimal device dimensions. In the mother liquor the silica particles exhibit zeta potentials < −60 mV, rendering them very stable even at high particle volume fractions. The current device typically produces around 0.234 g/h of the silica particles.